# Category : Science and Education

Archive : EPI_PAK.ZIP

Filename : EPI_PAK.DOC

A Collection of Epidemiologic Routines

Version 1.0, 8/June/1990

(c) 1990

by

Kevin M. Sullivan

Division of Nutrition

Centers for Disease Control

1600 Clifton Rd. NE, MS A08

Atlanta, GA 30333

Over the years I have developed a number of programs that

perform specific epidemiologic tasks and have combined

several of these together in Epi_Pak. The routines included

are:

MOWAN - calculates exact confidence interval for the odds

ratio from a single 2x2 table.

PAR - depicts the relationship between the Population

Attributable Risk and prevalence of exposure for a given

odds ratio.

PROPCI - uses several confidence interval procedures for

proportions.

RATECI - calculates approximate confidence interval for a

rate.

SAMPSIZE - performs samples size and power calculations.

SCREEN - calculates several screening indices from a 2x2

table.

I have been meaning to incorporate these into the program

dEpid but have not had the time. More detailed descriptions

of these programs are provided below.

MOWAN

See the MOWAN.DOC file for more details on this routine.

Please note that the FORTRAN code is not included with

Epi_Pak.

PAR

This program requests the entry of a risk ratio value and

then provides a graphic depicting the relationship between

the Population Attributable Risk (PAR - the proportion of

cases of a disease that are "attributable" to an

exposure/risk factor) and the prevalence of exposure. For

example, studies of the association between aspirin and Reye

syndrome have estimated that Reye syndrome is 20 times more

likely to develop in children who use aspirin. In 1980

approximately 50% of children received aspirin for the

treatment of colds and fever (prevalence of exposure = 50%).

Using PAR, you can see that for a risk ratio of 20, if the

prevalence of exposure is 50%, then about 90% of Reye

syndrome cases that occur in the population would be

attributed to the use of aspirin. If the prevalence of

aspirin use was reduced to 10%, then about 65% of the cases

of Reye syndrome that occur would be attributable to the use

of aspirin.

One option provided is whether you would like graphics.

If you answer (Y)es, a graph is provided using the higher

ASCII characters. If you answer (N)o, a character-based

graph is presented to the screen.

PROPCI

Please see the PROPCI.DOC file for information on this

routine.

RATECI

This program provides an approximate confidence interval

for a rate (i.e., person-time information). The confidence

interval formula is:

____

a | a

- + Z * | ---

N \| N*N

where:

a=number of cases

N=person-time

Z=Z value, e.g., for 95% confidence interval Z = 1.96

For example, say there were 15 cases during 19,017

person-years of follow-up. The point estimate would be 7.9

cases per 1000 person years with upper and lower 95%

confidence limits of 3.9 and 11.9 per 1000 person-years,

respectively.

SAMPSIZE

Please see the SAMPSIZE.DOC file for information on this

routine.

SCREEN

Please see the SCREEN.DOC file for information on this

routine.

Should you have any suggestions or comments, please

contact me.

DISTRIBUTION CONDITIONS

NON-WARRANTY. EPI_PAK is provided "as is" and without any

warranty expressed or implied. The user assumes all risks of

the use of EPI_PAK. EPI_PAK may not run on your particular

hardware/software configuration. We bear no responsibility

for any mishap or economic loss resulting therefrom the use

of this software.

COPYRIGHT CONDITIONS. You may make and distribute copies of

EPI_PAK provided that there is no material gain involved.

USE AT YOUR OWN RISK. All risk of loss of any kind due to

the use of EPI_PAK is with you, the user. You are

responsible for all mishaps, even if the program proves to

be defective. This program makes certain assumptions about

the data. These assumptions affect the validity of

conclusions made based on the output from this program.

Please acknowledge EPI_PAK in any manuscript that uses

its calculations.

Very nice! Thank you for this wonderful archive. I wonder why I found it only now. Long live the BBS file archives!

This is so awesome! 😀 I’d be cool if you could download an entire archive of this at once, though.

But one thing that puzzles me is the “mtswslnkmcjklsdlsbdmMICROSOFT” string. There is an article about it here. It is definitely worth a read: http://www.os2museum.com/wp/mtswslnk/